getent group nginx >/dev/null || groupadd -r nginx
getent passwd nginx >/dev/null || useradd -r -g nginx -s /sbin/nologin -d /var/cache/nginx -c "nginx user"  nginx

[Unit]
Description=nginx - high performance web server
Documentation=http://nginx.org/en/docs/
After=network.target remote-fs.target nss-lookup.target

[Service]
Type=forking
PIDFile=/run/nginx.pid
ExecStartPre=/usr/sbin/nginx -t -c /etc/nginx/nginx.conf
ExecStart=/usr/sbin/nginx -c /etc/nginx/nginx.conf
ExecReload=/bin/kill -s HUP $MAINPID
ExecStop=/bin/kill -s QUIT $MAINPID
PrivateTmp=true

[Install]
WantedBy=multi-user.target

user = <имя пользователя>

root@test-nginx:~# /usr/sbin/nginx

root@test-nginx:~# /opt/cprocsp/cp-openssl-1.1.0/bin/amd64/openssl engine
(rdrand) Intel RDRAND engine
(dynamic) Dynamic engine loading support
(gostengy) CryptoPro GostEngy ($Revision: 161714 $)

root@test-nginx:~# /usr/sbin/nginx -V
nginx version: nginx/1.12.1
built by gcc 5.4.0 20160609 (Ubuntu 5.4.0-6ubuntu1~16.04.1) 
built with OpenSSL 1.1.0g-dev  xx XXX xxxx
TLS SNI support enabled
configure arguments: --prefix=/etc/nginx --sbin-path=/usr/sbin/nginx --modules-path=/usr/lib/nginx/modules --conf-path=/etc/nginx/nginx.conf --error-log-path=/var/log/nginx/error.log --http-log-path=/var/log/nginx/access.log --http-client-body-temp-path=/var/cache/nginx/client_temp --http-proxy-temp-path=/var/cache/nginx/proxy_temp --http-fastcgi-temp-path=/var/cache/nginx/fastcgi_temp --http-uwsgi-temp-path=/var/cache/nginx/uwsgi_temp --http-scgi-temp-path=/var/cache/nginx/scgi_temp --pid-path=/var/run/nginx.pid --lock-path=/var/run/nginx.lock --user=root --group=nginx --user=nginx --group=nginx --with-compat --with-file-aio --with-threads --with-http_addition_module --with-http_auth_request_module --with-http_dav_module --with-http_flv_module --with-http_gunzip_module --with-http_gzip_static_module --with-http_mp4_module --with-http_random_index_module --with-http_realip_module --with-http_secure_link_module --with-http_slice_module --with-http_ssl_module --with-http_stub_status_module --with-http_sub_module --with-http_v2_module --with-mail --with-mail_ssl_module --with-stream --with-stream_realip_module --with-stream_ssl_module --with-stream_ssl_preread_module --with-cc-opt='-g -O2 -fstack-protector --param=ssp-buffer-size=4 -Wformat -Werror=format-security -Wp,-D_FORTIFY_SOURCE=2 -fPIC' --with-ld-opt='-Wl,-Bsymbolic-functions -Wl,-z,relro -Wl,-z,now -Wl,--as-needed -pie'

root@test-nginx:~# dpkg-query --list | grep csp
ii  cprocsp-compat-debian                      1.0.0-1                                                     all          CryptoPro CSP compatibility extension for non-LSB Debian/Ubuntu
ii  cprocsp-cpopenssl-110-64                   4.0.0-5                                                     amd64        OpenSSL-110. Build 9920.
ii  cprocsp-cpopenssl-110-base                 4.0.0-5                                                     all          Openssl-110 common Build 9920.
ii  cprocsp-cpopenssl-110-devel                4.0.0-5                                                     all          Openssl-110 devel Build 9920.
ii  cprocsp-cpopenssl-110-gost-64              4.0.0-5                                                     amd64        OpenSSL-110 capi_gost engine. Build 9920.
ii  cprocsp-curl-64                            4.0.0-5                                                     amd64        CryptoPro Curl shared library and binaris. Build 9914.
ii  lsb-cprocsp-base                           4.0.0-5                                                     all          CryptoPro CSP directories and scripts. Build 9914.
ii  lsb-cprocsp-capilite-64                    4.0.0-5                                                     amd64        CryptoAPI lite. Build 9914.
ii  lsb-cprocsp-kc1-64                         4.0.0-5                                                     amd64        CryptoPro CSP KC1. Build 9914.
ii  lsb-cprocsp-kc2-64                         4.0.0-5                                                     amd64        CryptoPro CSP KC2. Build 9914.
ii  lsb-cprocsp-rdr-64                         4.0.0-5                                                     amd64        CryptoPro CSP readers. Build 9914.

root@test-nginx:~# ps aux | grep nginx
root      4266  0.0  0.4  87340  7656 ?        Ss   16:33   0:00 nginx: master process /usr/sbin/nginx
root      4267  0.0  0.5  87804  8496 ?        S    16:33   0:00 nginx: worker process
root      4269  0.0  0.0  21292   988 pts/4    S+   16:34   0:00 grep --color=auto nginx

http://<ваш inet addr>

https://<ваш inet addr>